Diffraction-limited ultrasensitive molecular nano-arrays with singular nano-cone scattering
نویسندگان
چکیده
منابع مشابه
Diffraction-limited ultrasensitive molecular nano-arrays with singular nano-cone scattering.
Large-library fluorescent molecular arrays remain limited in sensitivity (1 × 10(6) molecules) and dynamic range due to background auto-fluorescence and scattering noise within a large (20-100 μm) fluorescent spot. We report an easily fabricated silica nano-cone array platform, with a detection limit of 100 molecules and a dynamic range that spans 6 decades, due to point (10 nm to 1 μm) illumin...
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ژورنال
عنوان ژورنال: Biomicrofluidics
سال: 2014
ISSN: 1932-1058
DOI: 10.1063/1.4869694